diff --git a/sysdeps/x86_64/multiarch/reg-macros.h b/sysdeps/x86_64/multiarch/reg-macros.h
new file mode 100644
index 0000000000..16168b6fda
--- /dev/null
+++ b/sysdeps/x86_64/multiarch/reg-macros.h
@@ -0,0 +1,166 @@
+/* This file was generated by: gen-reg-macros.py.
+
+   Copyright (C) 2022 Free Software Foundation, Inc.
+   This file is part of the GNU C Library.
+
+   The GNU C Library is free software; you can redistribute it and/or
+   modify it under the terms of the GNU Lesser General Public
+   License as published by the Free Software Foundation; either
+   version 2.1 of the License, or (at your option) any later version.
+
+   The GNU C Library is distributed in the hope that it will be useful,
+   but WITHOUT ANY WARRANTY; without even the implied warranty of
+   MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.  See the GNU
+   Lesser General Public License for more details.
+
+   You should have received a copy of the GNU Lesser General Public
+   License along with the GNU C Library; if not, see
+   <https://www.gnu.org/licenses/>.  */
+
+#ifndef _REG_MACROS_H
+#define _REG_MACROS_H	1
+
+#define rax_8	al
+#define rax_16	ax
+#define rax_32	eax
+#define rax_64	rax
+#define rbx_8	bl
+#define rbx_16	bx
+#define rbx_32	ebx
+#define rbx_64	rbx
+#define rcx_8	cl
+#define rcx_16	cx
+#define rcx_32	ecx
+#define rcx_64	rcx
+#define rdx_8	dl
+#define rdx_16	dx
+#define rdx_32	edx
+#define rdx_64	rdx
+#define rbp_8	bpl
+#define rbp_16	bp
+#define rbp_32	ebp
+#define rbp_64	rbp
+#define rsp_8	spl
+#define rsp_16	sp
+#define rsp_32	esp
+#define rsp_64	rsp
+#define rsi_8	sil
+#define rsi_16	si
+#define rsi_32	esi
+#define rsi_64	rsi
+#define rdi_8	dil
+#define rdi_16	di
+#define rdi_32	edi
+#define rdi_64	rdi
+#define r8_8	r8b
+#define r8_16	r8w
+#define r8_32	r8d
+#define r8_64	r8
+#define r9_8	r9b
+#define r9_16	r9w
+#define r9_32	r9d
+#define r9_64	r9
+#define r10_8	r10b
+#define r10_16	r10w
+#define r10_32	r10d
+#define r10_64	r10
+#define r11_8	r11b
+#define r11_16	r11w
+#define r11_32	r11d
+#define r11_64	r11
+#define r12_8	r12b
+#define r12_16	r12w
+#define r12_32	r12d
+#define r12_64	r12
+#define r13_8	r13b
+#define r13_16	r13w
+#define r13_32	r13d
+#define r13_64	r13
+#define r14_8	r14b
+#define r14_16	r14w
+#define r14_32	r14d
+#define r14_64	r14
+#define r15_8	r15b
+#define r15_16	r15w
+#define r15_32	r15d
+#define r15_64	r15
+
+#define kmov_8	kmovb
+#define kmov_16	kmovw
+#define kmov_32	kmovd
+#define kmov_64	kmovq
+#define kortest_8	kortestb
+#define kortest_16	kortestw
+#define kortest_32	kortestd
+#define kortest_64	kortestq
+#define kor_8	korb
+#define kor_16	korw
+#define kor_32	kord
+#define kor_64	korq
+#define ktest_8	ktestb
+#define ktest_16	ktestw
+#define ktest_32	ktestd
+#define ktest_64	ktestq
+#define kand_8	kandb
+#define kand_16	kandw
+#define kand_32	kandd
+#define kand_64	kandq
+#define kxor_8	kxorb
+#define kxor_16	kxorw
+#define kxor_32	kxord
+#define kxor_64	kxorq
+#define knot_8	knotb
+#define knot_16	knotw
+#define knot_32	knotd
+#define knot_64	knotq
+#define kxnor_8	kxnorb
+#define kxnor_16	kxnorw
+#define kxnor_32	kxnord
+#define kxnor_64	kxnorq
+#define kunpack_8	kunpackbw
+#define kunpack_16	kunpackwd
+#define kunpack_32	kunpackdq
+
+/* Common API for accessing proper width GPR is V{upcase_GPR_name}.  */
+#define VRAX	VGPR(rax)
+#define VRBX	VGPR(rbx)
+#define VRCX	VGPR(rcx)
+#define VRDX	VGPR(rdx)
+#define VRBP	VGPR(rbp)
+#define VRSP	VGPR(rsp)
+#define VRSI	VGPR(rsi)
+#define VRDI	VGPR(rdi)
+#define VR8	VGPR(r8)
+#define VR9	VGPR(r9)
+#define VR10	VGPR(r10)
+#define VR11	VGPR(r11)
+#define VR12	VGPR(r12)
+#define VR13	VGPR(r13)
+#define VR14	VGPR(r14)
+#define VR15	VGPR(r15)
+
+/* Common API for accessing proper width mask insn is {upcase_mask_insn}.  */
+#define KMOV 	VKINSN(kmov)
+#define KORTEST 	VKINSN(kortest)
+#define KOR 	VKINSN(kor)
+#define KTEST 	VKINSN(ktest)
+#define KAND 	VKINSN(kand)
+#define KXOR 	VKINSN(kxor)
+#define KNOT 	VKINSN(knot)
+#define KXNOR 	VKINSN(kxnor)
+#define KUNPACK 	VKINSN(kunpack)
+
+#ifndef REG_WIDTH
+# define REG_WIDTH VEC_SIZE
+#endif
+
+#define VPASTER(x, y)	x##_##y
+#define VEVALUATOR(x, y)	VPASTER(x, y)
+
+#define VGPR_SZ(reg_name, reg_size)	VEVALUATOR(reg_name, reg_size)
+#define VKINSN_SZ(insn, reg_size)	VEVALUATOR(insn, reg_size)
+
+#define VGPR(reg_name)	VGPR_SZ(reg_name, REG_WIDTH)
+#define VKINSN(mask_insn)	VKINSN_SZ(mask_insn, REG_WIDTH)
+
+#endif
diff --git a/sysdeps/x86_64/multiarch/scripts/gen-reg-macros.py b/sysdeps/x86_64/multiarch/scripts/gen-reg-macros.py
new file mode 100644
index 0000000000..c7296a8104
--- /dev/null
+++ b/sysdeps/x86_64/multiarch/scripts/gen-reg-macros.py
@@ -0,0 +1,123 @@
+#!/usr/bin/python3
+# Copyright (C) 2022 Free Software Foundation, Inc.
+# This file is part of the GNU C Library.
+#
+# The GNU C Library is free software; you can redistribute it and/or
+# modify it under the terms of the GNU Lesser General Public
+# License as published by the Free Software Foundation; either
+# version 2.1 of the License, or (at your option) any later version.
+#
+# The GNU C Library is distributed in the hope that it will be useful,
+# but WITHOUT ANY WARRANTY; without even the implied warranty of
+# MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.  See the GNU
+# Lesser General Public License for more details.
+#
+# You should have received a copy of the GNU Lesser General Public
+# License along with the GNU C Library; if not, see
+# <https://www.gnu.org/licenses/>.
+"""Generate macros for getting GPR name of a certain size
+
+Inputs: None
+Output: Prints header fill to stdout
+
+API:
+    VGPR(reg_name)
+        - Get register name VEC_SIZE component of `reg_name`
+    VGPR_SZ(reg_name, reg_size)
+        - Get register name `reg_size` component of `reg_name`
+"""
+
+import sys
+import os
+from datetime import datetime
+
+registers = [["rax", "eax", "ax", "al"], ["rbx", "ebx", "bx", "bl"],
+             ["rcx", "ecx", "cx", "cl"], ["rdx", "edx", "dx", "dl"],
+             ["rbp", "ebp", "bp", "bpl"], ["rsp", "esp", "sp", "spl"],
+             ["rsi", "esi", "si", "sil"], ["rdi", "edi", "di", "dil"],
+             ["r8", "r8d", "r8w", "r8b"], ["r9", "r9d", "r9w", "r9b"],
+             ["r10", "r10d", "r10w", "r10b"], ["r11", "r11d", "r11w", "r11b"],
+             ["r12", "r12d", "r12w", "r12b"], ["r13", "r13d", "r13w", "r13b"],
+             ["r14", "r14d", "r14w", "r14b"], ["r15", "r15d", "r15w", "r15b"]]
+
+mask_insns = [
+    "kmov",
+    "kortest",
+    "kor",
+    "ktest",
+    "kand",
+    "kxor",
+    "knot",
+    "kxnor",
+]
+mask_insns_ext = ["b", "w", "d", "q"]
+
+cr = """
+   Copyright (C) {} Free Software Foundation, Inc.
+   This file is part of the GNU C Library.
+
+   The GNU C Library is free software; you can redistribute it and/or
+   modify it under the terms of the GNU Lesser General Public
+   License as published by the Free Software Foundation; either
+   version 2.1 of the License, or (at your option) any later version.
+
+   The GNU C Library is distributed in the hope that it will be useful,
+   but WITHOUT ANY WARRANTY; without even the implied warranty of
+   MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.  See the GNU
+   Lesser General Public License for more details.
+
+   You should have received a copy of the GNU Lesser General Public
+   License along with the GNU C Library; if not, see
+   <https://www.gnu.org/licenses/>.  */
+"""
+
+print("/* This file was generated by: {}.".format(os.path.basename(
+    sys.argv[0])))
+print(cr.format(datetime.today().year))
+
+print("#ifndef _REG_MACROS_H")
+print("#define _REG_MACROS_H\t1")
+print("")
+for reg in registers:
+    for i in range(0, 4):
+        print("#define {}_{}\t{}".format(reg[0], 8 << i, reg[3 - i]))
+
+print("")
+for mask_insn in mask_insns:
+    for i in range(0, 4):
+        print("#define {}_{}\t{}{}".format(mask_insn, 8 << i, mask_insn,
+                                           mask_insns_ext[i]))
+for i in range(0, 3):
+    print("#define kunpack_{}\tkunpack{}{}".format(8 << i, mask_insns_ext[i],
+                                                   mask_insns_ext[i + 1]))
+mask_insns.append("kunpack")
+
+print("")
+print(
+    "/* Common API for accessing proper width GPR is V{upcase_GPR_name}.  */")
+for reg in registers:
+    print("#define V{}\tVGPR({})".format(reg[0].upper(), reg[0]))
+
+print("")
+
+print(
+    "/* Common API for accessing proper width mask insn is {upcase_mask_insn}.  */"
+)
+for mask_insn in mask_insns:
+    print("#define {} \tVKINSN({})".format(mask_insn.upper(), mask_insn))
+print("")
+
+print("#ifndef REG_WIDTH")
+print("# define REG_WIDTH VEC_SIZE")
+print("#endif")
+print("")
+print("#define VPASTER(x, y)\tx##_##y")
+print("#define VEVALUATOR(x, y)\tVPASTER(x, y)")
+print("")
+print("#define VGPR_SZ(reg_name, reg_size)\tVEVALUATOR(reg_name, reg_size)")
+print("#define VKINSN_SZ(insn, reg_size)\tVEVALUATOR(insn, reg_size)")
+print("")
+print("#define VGPR(reg_name)\tVGPR_SZ(reg_name, REG_WIDTH)")
+print("#define VKINSN(mask_insn)\tVKINSN_SZ(mask_insn, REG_WIDTH)")
+
+print("\n#endif")
