diff --git a/gcc/config/loongarch/loongarch-protos.h b/gcc/config/loongarch/loongarch-protos.h
index 83df489c7a5..b71b188507a 100644
--- a/gcc/config/loongarch/loongarch-protos.h
+++ b/gcc/config/loongarch/loongarch-protos.h
@@ -95,7 +95,7 @@ extern void loongarch_expand_conditional_trap (rtx);
 #endif
 extern void loongarch_set_return_address (rtx, rtx);
 extern bool loongarch_move_by_pieces_p (unsigned HOST_WIDE_INT, unsigned int);
-extern bool loongarch_expand_block_move (rtx, rtx, rtx);
+extern bool loongarch_expand_block_move (rtx, rtx, rtx, rtx);
 extern bool loongarch_do_optimize_block_move_p (void);
 
 extern bool loongarch_expand_ext_as_unaligned_load (rtx, rtx, HOST_WIDE_INT,
diff --git a/gcc/config/loongarch/loongarch.cc b/gcc/config/loongarch/loongarch.cc
index dfb731fca9d..06fc1cd0604 100644
--- a/gcc/config/loongarch/loongarch.cc
+++ b/gcc/config/loongarch/loongarch.cc
@@ -4459,41 +4459,38 @@ loongarch_function_ok_for_sibcall (tree decl ATTRIBUTE_UNUSED,
    Assume that the areas do not overlap.  */
 
 static void
-loongarch_block_move_straight (rtx dest, rtx src, HOST_WIDE_INT length)
+loongarch_block_move_straight (rtx dest, rtx src, HOST_WIDE_INT length,
+			       HOST_WIDE_INT delta)
 {
-  HOST_WIDE_INT offset, delta;
-  unsigned HOST_WIDE_INT bits;
+  HOST_WIDE_INT offs, delta_cur;
   int i;
   machine_mode mode;
   rtx *regs;
 
-  bits = MIN (BITS_PER_WORD, MIN (MEM_ALIGN (src), MEM_ALIGN (dest)));
-
-  mode = int_mode_for_size (bits, 0).require ();
-  delta = bits / BITS_PER_UNIT;
+  HOST_WIDE_INT num_reg = length / delta;
+  for (delta_cur = delta / 2; delta_cur != 0; delta_cur /= 2)
+    num_reg += !!(length & delta_cur);
 
   /* Allocate a buffer for the temporary registers.  */
-  regs = XALLOCAVEC (rtx, length / delta);
+  regs = XALLOCAVEC (rtx, num_reg);
 
-  /* Load as many BITS-sized chunks as possible.  Use a normal load if
-     the source has enough alignment, otherwise use left/right pairs.  */
-  for (offset = 0, i = 0; offset + delta <= length; offset += delta, i++)
+  for (delta_cur = delta, i = 0, offs = 0; offs < length; delta_cur /= 2)
     {
-      regs[i] = gen_reg_rtx (mode);
-      loongarch_emit_move (regs[i], adjust_address (src, mode, offset));
-    }
+      mode = int_mode_for_size (delta_cur * BITS_PER_UNIT, 0).require ();
 
-  for (offset = 0, i = 0; offset + delta <= length; offset += delta, i++)
-    loongarch_emit_move (adjust_address (dest, mode, offset), regs[i]);
+      for (; offs + delta_cur <= length; offs += delta_cur, i++)
+	{
+	  regs[i] = gen_reg_rtx (mode);
+	  loongarch_emit_move (regs[i], adjust_address (src, mode, offs));
+	}
+    }
 
-  /* Mop up any left-over bytes.  */
-  if (offset < length)
+  for (delta_cur = delta, i = 0, offs = 0; offs < length; delta_cur /= 2)
     {
-      src = adjust_address (src, BLKmode, offset);
-      dest = adjust_address (dest, BLKmode, offset);
-      move_by_pieces (dest, src, length - offset,
-		      MIN (MEM_ALIGN (src), MEM_ALIGN (dest)),
-		      (enum memop_ret) 0);
+      mode = int_mode_for_size (delta_cur * BITS_PER_UNIT, 0).require ();
+
+      for (; offs + delta_cur <= length; offs += delta_cur, i++)
+	loongarch_emit_move (adjust_address (dest, mode, offs), regs[i]);
     }
 }
 
@@ -4523,10 +4520,11 @@ loongarch_adjust_block_mem (rtx mem, HOST_WIDE_INT length, rtx *loop_reg,
 
 static void
 loongarch_block_move_loop (rtx dest, rtx src, HOST_WIDE_INT length,
-			   HOST_WIDE_INT bytes_per_iter)
+			   HOST_WIDE_INT align)
 {
   rtx_code_label *label;
   rtx src_reg, dest_reg, final_src, test;
+  HOST_WIDE_INT bytes_per_iter = align * LARCH_MAX_MOVE_OPS_PER_LOOP_ITER;
   HOST_WIDE_INT leftover;
 
   leftover = length % bytes_per_iter;
@@ -4546,7 +4544,7 @@ loongarch_block_move_loop (rtx dest, rtx src, HOST_WIDE_INT length,
   emit_label (label);
 
   /* Emit the loop body.  */
-  loongarch_block_move_straight (dest, src, bytes_per_iter);
+  loongarch_block_move_straight (dest, src, bytes_per_iter, align);
 
   /* Move on to the next block.  */
   loongarch_emit_move (src_reg,
@@ -4563,7 +4561,7 @@ loongarch_block_move_loop (rtx dest, rtx src, HOST_WIDE_INT length,
 
   /* Mop up any left-over bytes.  */
   if (leftover)
-    loongarch_block_move_straight (dest, src, leftover);
+    loongarch_block_move_straight (dest, src, leftover, align);
   else
     /* Temporary fix for PR79150.  */
     emit_insn (gen_nop ());
@@ -4573,25 +4571,32 @@ loongarch_block_move_loop (rtx dest, rtx src, HOST_WIDE_INT length,
    memory reference SRC to memory reference DEST.  */
 
 bool
-loongarch_expand_block_move (rtx dest, rtx src, rtx length)
+loongarch_expand_block_move (rtx dest, rtx src, rtx r_length, rtx r_align)
 {
-  int max_move_bytes = LARCH_MAX_MOVE_BYTES_STRAIGHT;
+  if (!CONST_INT_P (r_length))
+    return false;
+
+  HOST_WIDE_INT length = INTVAL (r_length);
+  if (length > loongarch_max_inline_memcpy_size)
+    return false;
+
+  HOST_WIDE_INT align = INTVAL (r_align);
+
+  if (!TARGET_STRICT_ALIGN || align > UNITS_PER_WORD)
+    align = UNITS_PER_WORD;
 
-  if (CONST_INT_P (length)
-      && INTVAL (length) <= loongarch_max_inline_memcpy_size)
+  if (length <= align * LARCH_MAX_MOVE_OPS_STRAIGHT)
     {
-      if (INTVAL (length) <= max_move_bytes)
-	{
-	  loongarch_block_move_straight (dest, src, INTVAL (length));
-	  return true;
-	}
-      else if (optimize)
-	{
-	  loongarch_block_move_loop (dest, src, INTVAL (length),
-				     LARCH_MAX_MOVE_BYTES_PER_LOOP_ITER);
-	  return true;
-	}
+      loongarch_block_move_straight (dest, src, length, align);
+      return true;
+    }
+
+  if (optimize)
+    {
+      loongarch_block_move_loop (dest, src, length, align);
+      return true;
     }
+
   return false;
 }
 
diff --git a/gcc/config/loongarch/loongarch.h b/gcc/config/loongarch/loongarch.h
index 7151d5cabb3..1bcd144a5d9 100644
--- a/gcc/config/loongarch/loongarch.h
+++ b/gcc/config/loongarch/loongarch.h
@@ -1063,13 +1063,13 @@ typedef struct {
 
 /* The maximum number of bytes that can be copied by one iteration of
    a cpymemsi loop; see loongarch_block_move_loop.  */
-#define LARCH_MAX_MOVE_BYTES_PER_LOOP_ITER (UNITS_PER_WORD * 4)
+#define LARCH_MAX_MOVE_OPS_PER_LOOP_ITER 4
 
 /* The maximum number of bytes that can be copied by a straight-line
    implementation of cpymemsi; see loongarch_block_move_straight.  We want
    to make sure that any loop-based implementation will iterate at
    least twice.  */
-#define LARCH_MAX_MOVE_BYTES_STRAIGHT (LARCH_MAX_MOVE_BYTES_PER_LOOP_ITER * 2)
+#define LARCH_MAX_MOVE_OPS_STRAIGHT (LARCH_MAX_MOVE_OPS_PER_LOOP_ITER * 2)
 
 /* The base cost of a memcpy call, for MOVE_RATIO and friends.  These
    values were determined experimentally by benchmarking with CSiBE.
@@ -1077,7 +1077,7 @@ typedef struct {
 #define LARCH_CALL_RATIO 8
 
 /* Any loop-based implementation of cpymemsi will have at least
-   LARCH_MAX_MOVE_BYTES_STRAIGHT / UNITS_PER_WORD memory-to-memory
+   LARCH_MAX_MOVE_OPS_PER_LOOP_ITER memory-to-memory
    moves, so allow individual copies of fewer elements.
 
    When cpymemsi is not available, use a value approximating
@@ -1088,9 +1088,7 @@ typedef struct {
    value of LARCH_CALL_RATIO to take that into account.  */
 
 #define MOVE_RATIO(speed) \
-  (HAVE_cpymemsi \
-   ? LARCH_MAX_MOVE_BYTES_PER_LOOP_ITER / UNITS_PER_WORD \
-   : CLEAR_RATIO (speed) / 2)
+  (HAVE_cpymemsi ? LARCH_MAX_MOVE_OPS_PER_LOOP_ITER : CLEAR_RATIO (speed) / 2)
 
 /* For CLEAR_RATIO, when optimizing for size, give a better estimate
    of the length of a memset call, but use the default otherwise.  */
diff --git a/gcc/config/loongarch/loongarch.md b/gcc/config/loongarch/loongarch.md
index 628ecc78088..816a943d155 100644
--- a/gcc/config/loongarch/loongarch.md
+++ b/gcc/config/loongarch/loongarch.md
@@ -2488,7 +2488,8 @@ (define_expand "cpymemsi"
   ""
 {
   if (TARGET_DO_OPTIMIZE_BLOCK_MOVE_P
-      && loongarch_expand_block_move (operands[0], operands[1], operands[2]))
+      && loongarch_expand_block_move (operands[0], operands[1],
+				      operands[2], operands[3]))
     DONE;
   else
     FAIL;
diff --git a/gcc/testsuite/gcc.target/loongarch/pr109465-1.c b/gcc/testsuite/gcc.target/loongarch/pr109465-1.c
new file mode 100644
index 00000000000..4cd35d13904
--- /dev/null
+++ b/gcc/testsuite/gcc.target/loongarch/pr109465-1.c
@@ -0,0 +1,9 @@
+/* { dg-do compile } */
+/* { dg-options "-O2 -mabi=lp64d -mno-strict-align" } */
+/* { dg-final { scan-assembler-times "st\\.d|stptr\\.d" 1 } } */
+/* { dg-final { scan-assembler-times "st\\.w|stptr\\.w" 1 } } */
+/* { dg-final { scan-assembler-times "st\\.h" 1 } } */
+/* { dg-final { scan-assembler-times "st\\.b" 1 } } */
+
+extern char a[], b[];
+void test() { __builtin_memcpy(a, b, 15); }
diff --git a/gcc/testsuite/gcc.target/loongarch/pr109465-2.c b/gcc/testsuite/gcc.target/loongarch/pr109465-2.c
new file mode 100644
index 00000000000..703eb951c6d
--- /dev/null
+++ b/gcc/testsuite/gcc.target/loongarch/pr109465-2.c
@@ -0,0 +1,9 @@
+/* { dg-do compile } */
+/* { dg-options "-O2 -mabi=lp64d -mstrict-align" } */
+/* { dg-final { scan-assembler-times "st\\.d|stptr\\.d" 1 } } */
+/* { dg-final { scan-assembler-times "st\\.w|stptr\\.w" 1 } } */
+/* { dg-final { scan-assembler-times "st\\.h" 1 } } */
+/* { dg-final { scan-assembler-times "st\\.b" 1 } } */
+
+extern long a[], b[];
+void test() { __builtin_memcpy(a, b, 15); }
diff --git a/gcc/testsuite/gcc.target/loongarch/pr109465-3.c b/gcc/testsuite/gcc.target/loongarch/pr109465-3.c
new file mode 100644
index 00000000000..d6a80659b31
--- /dev/null
+++ b/gcc/testsuite/gcc.target/loongarch/pr109465-3.c
@@ -0,0 +1,12 @@
+/* { dg-do compile } */
+/* { dg-options "-O2 -mabi=lp64d -mstrict-align" } */
+
+/* Three loop iterations each contains 4 st.b, and 3 st.b after the loop */
+/* { dg-final { scan-assembler-times "st\\.b" 7 } } */
+
+/* { dg-final { scan-assembler-not "st\\.h" } } */
+/* { dg-final { scan-assembler-not "st\\.w|stptr\\.w" } } */
+/* { dg-final { scan-assembler-not "st\\.d|stptr\\.d" } } */
+
+extern char a[], b[];
+void test() { __builtin_memcpy(a, b, 15); }
